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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 19.39
Human Site: S1066 Identified Species: 35.56
UniProt: P39880 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P39880 NP_853530.2 1505 164273 S1066 S P M S S S E S V K S L T E L
Chimpanzee Pan troglodytes XP_527845 1515 165612 S1077 S P M S S S E S V K S L T E L
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 S1343 S P M S S S E S V K S L T E L
Dog Lupus familis XP_546939 1411 154543 P1007 P T R P P S R P P D P S P I E
Cat Felis silvestris
Mouse Mus musculus P53564 1515 165577 S1061 S P M S S S E S V K S L T E L
Rat Rattus norvegicus P53565 862 92341 S465 I Q E L V A M S P E L D T Y G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 L1057 S S Q E P L G L N L E S S K E
Chicken Gallus gallus XP_425393 1673 183755 S1205 S P M S S S E S V K S L T E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 D947 S P P A S P A D A Q S S T V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 L1557 P P Q H A I S L P P S A G G A
Honey Bee Apis mellifera XP_623857 1936 209316 G1443 P M M L T P P G P H H P H A Q
Nematode Worm Caenorhab. elegans Q9BL02 1273 143507 V876 L G L S Q G S V S D L L A R P
Sea Urchin Strong. purpuratus XP_780858 1460 163719 L1034 T Q Q V K N L L Q Q H G L G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 83.1 56.2 N.A. 88.8 47.1 N.A. 44.3 77.4 N.A. 40.9 N.A. 23.3 23.7 22.3 29.1
Protein Similarity: 100 98.6 83.4 64.5 N.A. 91.8 50 N.A. 60 81.7 N.A. 55.4 N.A. 37.4 41 41 46.6
P-Site Identity: 100 100 100 6.6 N.A. 100 13.3 N.A. 6.6 100 N.A. 40 N.A. 13.3 6.6 13.3 0
P-Site Similarity: 100 100 100 6.6 N.A. 100 26.6 N.A. 20 100 N.A. 53.3 N.A. 20 13.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 8 0 8 0 0 8 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 16 0 8 0 0 0 % D
% Glu: 0 0 8 8 0 0 39 0 0 8 8 0 0 39 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 8 8 0 0 0 8 8 16 8 % G
% His: 0 0 0 8 0 0 0 0 0 8 16 0 8 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 39 0 0 0 8 0 % K
% Leu: 8 0 8 16 0 8 8 24 0 8 16 47 8 0 47 % L
% Met: 0 8 47 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 24 54 8 8 16 16 8 8 31 8 8 8 8 0 8 % P
% Gln: 0 16 24 0 8 0 0 0 8 16 0 0 0 0 16 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % R
% Ser: 54 8 0 47 47 47 16 47 8 0 54 24 8 0 0 % S
% Thr: 8 8 0 0 8 0 0 0 0 0 0 0 54 0 0 % T
% Val: 0 0 0 8 8 0 0 8 39 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _